Goals from Cody Gakpo and Frenkie De Jong ensured the Netherlands topped Group A after easing past the hosts Qatar 2-0.
Qatar have lost all three of their group games, cementing them as the worst performing host nation in World Cup history.
Louis Van Gaal is in his third stint as Netherlands manager and is now unbeaten in 18 games.
The first half was dominated by the Netherlands as they piled the pressure on a disjointed Qatari defence. Memphis Depay, who returned to the starting line-up, had numerous early chances, but he was unable to find the target.
The substitute Steven Berghuis was denied a goal in the 68th minute as VAR decided Gakpo handled the ball in the build-up.
Next up for the Netherlands is a last 16 clash against the runners-up of Group B on Sunday.